Pesticides in the Blood Samples of Spray-workers at Agriculture Environment: The Toxicological Evaluation
Pesticides are major contaminating chemicals in agriculture environment and a hazard to exposed population. These compounds are absorbed by inhalation, ingestion, and dermal contact. Their bioavailability in the individuals can lead to a variety of metabolic and systemic dysfunctions, and even outright disease states. Therefore, the tremendous usage of pesticides has promoted toxicological studies in spraying community. This study comprising pesticide spray-workers (n=140) and controls (n=110) indicated highly significant effects by analytical means on serum cholinesterase level (p<0.001) through ANOVA. Duncan Multiple Range Test ranking for monocrotophos and carbaryl were similar though different than endosulfan and cypermethrin, which conceptualized the effects on cholinesterase level. The GC-MS detection of residue concentrations in blood serum samples of spray-workers; calculated for endosulfan, monocrotophos, carbaryl and cypermethrin were 0.009, 0.005, 0.05 and 0.08 mg/kg body weight respectively. It was further seen in light of reported NOAEL that indicated the effect and extent of exposure among the study population.
Submission of a manuscript to the Journal will be taken to imply that:
- The work is original and has not been previously published (except in the form of an abstract or a part of a published lecture, review or thesis).
- It is not being considered for publication elsewhere, and
- If accepted for publication, it will NOT be published commercially elsewhere in the same form, in any language, without the consent of Editor or Publisher.