Measurement of Densities and Partial Molar Volume of Paracetamol in different media
Abstract
The partial molar volume of Paracetamol (4-acetamidophenol) in water, 0.1 M HCl solution and 0.9% NaCl solution at 298.15K, 303.15 K, 308.15 K and 310.15 K have been evaluated with the help of vibrating tube densitimeter Anton Paar (DMA 48). The effect of 0.1 M HCl solution whose pH is comparable with the pH of stomach and 0.9% NaCl solution is comparable with the isotonic solution of human fluid were checked. The results were fitted by the regression to equation that describe the plot (V, T, m). At infinite dilution, partial molar volumes were obtained over the range of temperature by extrapolating these plots to m = 0 mol/kg
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