Carbamates Toxicity in Farmers and its Assessment Through Biochemical Parameters

  • A. M Soomro 1Faculty of Pharmacy, University of Sindh, Jamshoro, Pakistan
  • G. M Seehar Department of Physiology, University of Sindh, Jamshoro, Pakistan
  • M. I Bhanger National Center of Excellence in Analytical Chemistry, University of Sindh, Jamshoro, Pakistan

Abstract

Prevalent environmental toxicity of various chemical groups of pesticides and their effects leading towards increasing morbidity and mortality in the farmers is of great concerned. In this situation the biochemical biomarkers are regarded as meaningful tools for monitoring toxic end points. This work was aimed to assess the toxic impacts of carbamates through some biochemical parameters and useful validity of these biomarkers was also observed. Present results reveal inhibition of cholinesterase activity by 46%, whereas bilirubin, urea and creatinine levels in serum were increased and sugar values was decreased at highly significant level (p<0.001). Urine urobilinogen concentration found raised significantly at high level (p<0.001) while protein, urea, creatinine and sugar values in urine of the farmers seen non-significant. This study concluded that the selected biochemical parameters can be used as biomarkers to assess the significant toxic effects in the exposed populations. 

Published
Dec 1, 2005
How to Cite
SOOMRO, A. M; SEEHAR, G. M; BHANGER, M. I. Carbamates Toxicity in Farmers and its Assessment Through Biochemical Parameters. Pakistan Journal of Analytical & Environmental Chemistry, [S.l.], v. 6, n. 2, p. 4, dec. 2005. ISSN 2221-5255. Available at: <http://pjaec.pk/index.php/pjaec/article/view/108>. Date accessed: 14 aug. 2018.