Synthesis, Characterization and Antioxidant Activity of Rutin Complexes

Qadeer K. Panhwar; Shahabuddin Memon

doi:10.21743/

Authors

Qadeer K. Panhwar Dr. M. A. Kazi Institute of Chemistry, University of Sindh, Jamshoro, Pakistan Author
Shahabuddin Memon National Centre of Excellence in Analytical Chemistry, University of Sindh, Jamshoro 76080, Pakistan Author

DOI:

https://doi.org/10.21743/

Keywords:

Rutin; Zr(IV)-Rutin Complex; Mo(VI)-Rutin Complex; Antioxidant

Abstract

Rutin, one of the excellent chelating agents, has been made to react with Zr⁴⁺ and MoO₄^2- ions to get metal complexes in methanol. The synthesis, spectral properties (UV-Vis, 1H NMR, 13C NMR, IR), thermal behavior and antioxidant activity of these complexes have been studied. It has been observed that rutin forms deep yellow colored complexes of mononuclear composition (through 5OH-4CO system in case of Zr⁴⁺/catechol site in case of MoO₄^2-) having stoichiometry, 1:2 and 1:1 for Zr⁴⁺ and MoO₄^2- ions, respectively. It has been further noticed that these complexes are formed at different pHs, i.e. 4.0 and 8.0 pHs suitable for Zr⁴⁺ and MoO₄^2- complexes, respectively. Thermograms also confirm the results of IR and support the presence of water molecules in complexes. Relative antioxidant activity of the rutin ligand, zirconium-rutin and molybdenumrutin complexes was determined. It was found that both metal complexes have higher antioxidant activity than rutin alone.