Determination of Total Phenolic, Flavonoid Content and Antimicrobial Properties in Different Solvent Extracts of Viburnum opulus L. (Gilaburu) in Afyonkarahisar

Abstract

This study determined the antimicrobial and antioxidant activities of chloroform, ethyl acetate, methanol, and water extracts of the Viburnum opulus (V. opulus) plant. V. opulus (Gilaburu) was collected from Ahırdağı northern slope, Kırka Town, Afyonkarahisar region, and its leaves, branches, and fruit parts were dried and powdered at room temperature. The total phenolic content was compared with the gallic acid standard, the total flavonoid content with the quercetin standard, and the iron chelating effect with the EDTA standard. All extracts were evaluated for antimicrobial activity against Escherichia coli, Staphyllococcus aureus, and Candida glabrata strains by the agar well diffusion method. Gilaburu is widely used in Turkey, especially in alternative medicine. It has been determined that the fruit part of the plant has better antimicrobial properties, and the amount of phenolic compounds increases in more polar solvents. In conclusion, the use of Gilaburu as a medicinal drug can be achieved with new research on bioactive substances, especially in fruit extract