5,7-Dihydroxy-2-(4-hydroxyphenyl)chroman-4-one Functionalized CuO Nanoparticles: Synthesis, Characterization and Antioxidant Activity

Qadeer Khan Panhwar; Aamna Balouch; Ali Nawaz Siyal; Farida Shaikh; Sanaullah Dehraj; Wazir Ali Panhwar; Aqsa Ahmed

doi:10.21743/pjaec/2020.06.13

Authors

Qadeer Khan Panhwar Dr. M. A. Kazi Institute of Chemistry, University of Sindh, Jamshoro 76080, Pakistan Author
Aamna Balouch National Centre of Excellence in Analytical Chemistry, University of Sindh, Jamshoro, Pakistan Author
Ali Nawaz Siyal Dr. M. A. Kazi Institute of Chemistry, University of Sindh, Jamshoro 76080, Pakistan Author
Farida Shaikh Dr. M. A. Kazi Institute of Chemistry, University of Sindh, Jamshoro 76080, Pakistan Author
Sanaullah Dehraj Department of Basic Science and Related Studies, Quaid-E-Awam University of Engineering, Science and Technology 67480, Nawab Shah, Pakistan Author
Wazir Ali Panhwar Institute of Physics, University of Sindh, Jamshoro 76080, Pakistan Author
Aqsa Ahmed Department of Chemistry, University of Engineering and Technology, Lahore 54890, Pakistan Author

DOI:

https://doi.org/10.21743/pjaec/2020.06.13

Keywords:

CuO nanoparticles, Naringenin, Antioxidant activity, DPPH

Abstract

Naringenin (NaR) is a flavonoid, mostly found in citrus fruit. Its IUPAC name is 5,7-Dihydroxy-2-(4-hydroxyphenyl)chroman-4-one. Naringenin is lipophilic in nature and possessing antioxidant property. In present study,7-Dihydroxy-2-(4-hydroxyphenyl)chroman-4-one was incorporated onto CuO nanoparticles (CuO-NPs) for enhancing its antioxidant activity. The CuO-NPs and its functionalized form (CuO-NaR) were characterized by Fourier-transform infrared (FT-IR) spectroscopy, X-ray diffraction (XRD), Scanning electron microscope (SEM) and Energy dispersive X-ray (EDX) analysis. The CuO-NPs, CuO-NaR and NaR were examined for their comparative antioxidant activities followed by DPPH (2,2-Diphenyl-1-picrylhydrazyl) method. The results revealed that the antioxidant activity of CuO-NaR was enhanced significantly.